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The difference between Porous chilli plaster and ordinary pa

Time:2018-06-19 16:55
First of all, we need to understand what is the  chilli plaster: Chilli plaster is a topical patch. It has a long history of application in Japan. After it is mixed with herbs or chemicals, it is mixed with a suitable hydrophilic matrix and coated on the back. Plaster made of a lining material. It is composed of a backing (commonly used non-woven cloth, elastic cloth, spunlace cloth), a paste, and a release film (a release film on the surface of the paste). Its drug loading is large, moisture retention is strong, compatibility with the skin is good, and it is resistant to aging. It can be used repeatedly to stop the administration at any time, and the measurement is accurate. The blood concentration balance has no peaks and valleys and can reduce toxic side effects in industrial production. There is no organic solvent pollution and environmental protection requirements.
The chilli plaster is a topical patch made of a water-soluble polymer material or a hydrophilic substance as a base and a drug. The chilli plaster substrate must not only have a certain viscosity, but also have spreadability, uniformity, and flexibility. Because of the different properties of the components, the role in the matrix is ??different, and the difference in the amount of addition is determined, so the composition of each ingredient is reasonable. The ratio is the key to making a good matrix.
The chilli plaster is divided into two types, a mud-like patching agent and a stereotyped patching agent. Muddy rags are generally based on glycerin, gelatin, water, etc., and the drug and the matrix are mixed. The drug is applied to the denuded cotton, adhered to the affected part, and fixed with a bandage, which is somewhat similar to the ointment. The matrix of stereotype chilli plaster is commonly used water-soluble high-molecular substances such as glycerin, gelatin, methyl cellulose, and polyacrylic acid. The drug and the base are mixed and coated on a non-woven fabric, and the surface is covered with a polyethylene or polypropylene film. Use requirements cut into different specifications, into a plastic or paper bag, paste it on the affected area when used, similar to plaster.
Compared with traditional plasters, chilli plaster have unique advantages:
The matrix load of chilli plaster is compatible with water-soluble and fat-soluble drugs, which is very suitable for the characteristics of multi-component and high-dose drugs, has no effect on the stability of the main drug, no side effects, no irritation and allergy to the skin. The reaction does not remain on the skin. The breathability, adhesion to the skin, and heat preservation of the chili paste plaster are superior to those of traditional plasters. Therefore, it is comfortable to use, can be repeatedly exposed and applied, does not contaminate clothing, and has no residue. The painlessness and other advantages are revealed; the practical method of the chili paste plaster is simple, the customer can feel cool and pleasant, there is no sense of discomfort, especially suitable for summer patching; compared with the oral dosage form, there is no hepatic first-pass effect and is not subject to degradation of the gastrointestinal tract Impact, high bioavailability.
chilli plaster